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Does Wegovy need to be refrigerated?

Medical News Today Published Jun 15, 2026 Reviewed Jul 2, 2026 ✓ Reviewed by citations.press editors
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Wegovy pens and syringes in the U.S. contain one dose and must be discarded after use.
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In most other countries, Wegovy is supplied in FlexTouch pens containing four doses, so you don’t discard them until you’ve used the fourth dose.
4 · dose
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The 7.2 mg dose is supplied in a single-use pen or syringe in all countries.
7.2 mg · dose
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Room temperature limit for Wegovy is up to 86°F (30°C).
up to 86 ºF · room temperature limitup to 30 ºC · room temperature limit
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The storage temperature for prefilled single-dose pens or syringes should stay between 36°F and 46°F (2°C to 8°C).
at least 36 ºF · storage temperatureat most 46 ºF · storage temperatureat least 2 ºC · storage temperatureat most 8 ºC · storage temperature
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An unopened single-use Wegovy pen or syringe can be stored at room temperature below 86°F (30°C) for up to 28 days if the cap has not been removed.
up to 28 days · storage durationbelow 86 ºF · room temperature limitbelow 30 ºC · room temperature limit
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Most Wegovy FlexTouch pens (0.25 mg to 2.4 mg) can be stored at room temperature below 86°F (30°C) for up to 6 weeks.
at least 0.25 mg · doseat most 2.4 mg · doseup to 6 weeks · storage durationbelow 86 ºF · room temperature limitbelow 30 ºC · room temperature limit
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The 7.2 mg dose comes in a single-use pen and can be stored at room temperature for up to 28 days if necessary.
7.2 mg · doseup to 28 days · storage duration
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Wegovy pills should be stored at room temperature between 68°F and 77°F (20°C to 25°C).
at least 68 °F · room temperatureat most 77 °F · room temperatureat least 20 ºC · room temperatureat most 25 ºC · room temperature
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In the U.S., Wegovy can be kept at room temperature for up to 28 days if a fridge is not available.
up to 28 days · storage duration
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Outside of the U.S., most Wegovy pens can be stored at room temperature for up to 6 weeks.
up to 6 weeks · storage duration
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Wegovy must never be allowed to freeze or get hotter than 86°F (30°C).
above 86 ºF · temperature limitabove 30 ºC · temperature limit
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The storage guidelines for Wegovy depend on the type of pen you have and where you live.

The ideal place to store Wegovy pens and syringes is in the fridge. However, the rules for storing the medication at room temperature differ depending on whether you’re using the multidose pens, which are common outside the United States, or the single-dose pens or syringes, which are used in the U.S.

This article explains how to store Wegovy, what to do with it when you travel, and how to tell whether it’s safe to use.

Different types of Wegovy pens and syringes are available in different countries, so the storage guidelines also differ.

In the U.S., Wegovy pens and syringes contain one dose and must be discarded after use. In most other countries, Wegovy is supplied in FlexTouch pens containing four doses, so you don’t discard them until you’ve used the fourth dose. The 7.2 mg dose is an exception, as that is supplied in a single-use pen or syringe in all countries.

The table below summarizes the Wegovy storage guidelines. The following sections explain them in more detail.

The best place to store Wegovy prefilled single-dose pens or syringes is in the refrigerator. The temperature should stay between 36ºF and 46ºF (2ºC to 8ºC). This temperature helps keep the medication stable so it works effectively.

When you put your pens in the fridge, try to keep them in their original box. The box is designed to protect the medication from light, which can break down the ingredients and make them less effective.

If necessary, an unopened single-use Wegovy pen or syringe can be stored at room temperature (below 86ºF/ 30ºC) for up to 28 days, provided the cap has not been removed.

As soon as you remove the cap, give yourself the injection, then discard the pen.

The ideal way to store FlexTouch pens is in the fridge between 36ºF and 46ºF (2ºC to 8ºC).

If necessary, you can keep most Wegovy FlexTouch pens (0.25 mg to 2.4 mg) at room temperature (below 86ºF/ 30ºC) for up to 6 weeks. You can also take the pen out of the fridge and leave it at room temperature for up to 6 weeks.

If possible, refrigerate your Wegovy pen when you first get it and return it to the fridge right after each injection. Make sure you’ve removed the needle, replaced the cap, and put it back in its box.

Once you’ve had your last dose, dispose of the pen in a sharps container.

The 7.2 mg dose comes in a single-use pen, which, ideally, should be stored in the fridge. If necessary, it can be stored at room temperature for up to 28 days and then discarded after use.

Before every injection, check your medication in the window on the side of the device. Follow this guidance to determine whether your medication is safe or unsafe to use:

If your pen or syringe shows signs that it’s not safe to use, do not use it and contact Wegovy’s Patient Customer Care Center at 1-833-934-6891 for a replacement.

Yes, you can still use it as long as the room didn’t get hotter than 86°F (30 ºC) overnight. Once it’s been at room temperature, you must use it within 28 days.

Yes, you can still use it as long as the room didn’t get hotter than 86°F (30 ºC) overnight. Once it’s been at room temperature, you must use it within 28 days.

If your Wegovy pen freezes, throw it away. Freezing changes the medication and can make it unsafe or ineffective.

If your Wegovy pen freezes, throw it away. Freezing changes the medication and can make it unsafe or ineffective.

Yes, you can return Wegovy to the fridge, but you still have to use it within 28 days from the time it warmed up to room temperature.

Yes, you can return Wegovy to the fridge, but you still have to use it within 28 days from the time it warmed up to room temperature.

Yes, you can inject cold Wegovy. However, if you find that injecting cold medication is uncomfortable, you can let it sit out for a short time to reach room temperature. Never try to warm it up using a microwave, hot water, or any other heat source, as this will damage the medication.

Yes, you can inject cold Wegovy. However, if you find that injecting cold medication is uncomfortable, you can let it sit out for a short time to reach room temperature. Never try to warm it up using a microwave, hot water, or any other heat source, as this will damage the medication.

Store Wegovy pills at room temperature (68°F to 77°F/ 20ºC to 25ºC) in a dry place. Keep them in their original bottle with the lid on.

Store Wegovy pills at room temperature (68°F to 77°F/ 20ºC to 25ºC) in a dry place. Keep them in their original bottle with the lid on.

To keep Wegovy working its best, store your injection pens or syringes in the fridge and keep them inside their original box to block out light.

In the U.S., you can keep Wegovy at room temperature for up to 28 days if a fridge is not available.

Outside of the U.S, you can store most Wegovy pens at room temperature for up to 6 weeks. Regardless of where you live, you must never allow Wegovy to freeze or get hotter than 86ºF (30ºC).

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