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Moderna Shares Skyrocket 90% Toward Best Day Ever—Here’s Why

Forbes Published Aug 19, 2026 Reviewed Aug 19, 2026 ✓ Reviewed by citations.press editors
Moderna Shares Skyrocket 90% Toward Best Day Ever—Here’s Why
Moderna’s stock surged by more than 90% as trading opened Wednesday, nearly doubling the biotech giant’s share price after the firm announced positive results from its first-ever late-stage trial of an experimental cancer vaccine.
more than 90 % · Moderna's stock
Shares of Moderna rocketed by 93% to around $121.90 on Wednesday, pacing what would be the stock’s best-ever trading session after surging by more than 100% in premarket trading.
93 % · Shares of Moderna121.9 $ · Shares of Moderna
The personalized cancer vaccine helped cut recurrence of melanoma in a late-stage trial involving more than 1,100 patients.
more than 1100 patients · personalized cancer vaccine trial
Merck’s stock jumped 6.5% in early trading following the announcement.
6.5 % · Merck's stock
112,000 new cases of melanoma are diagnosed in the U.S. each year, with about 8,510 people expected to die of melanoma, according to the American Cancer Society.
112000 cases · melanoma cases in U.S.about 8510 deaths · melanoma deaths in U.S. American Cancer Society, source
The lowest level for Moderna’s stock came during its first trading session this year, dropping to $29.81 on Jan. 2 before surging nearly 300% to its premarket value on Wednesday.
29.81 $ · Moderna's stockmore than 300 % · Moderna's stock
Health and Human Services Secretary Robert F. Kennedy Jr. said he would cancel contracts and grants worth nearly $500 million to develop such vaccines.
more than 500000000 $ · contracts and grants Health and Human Services Secretary Robert F. Kennedy Jr., Secretary

Moderna’s stock soared by more than 90% as trading opened Wednesday, nearly doubling the biotech giant’s share price after the firm announced positive results from its first-ever late-stage trial of an experimental cancer vaccine.

Shares of Moderna rocketed by 93% to around $121.90 on Wednesday, pacing what would be the stock’s best-ever trading session after surging by more than 100% in premarket trading.

That came after Moderna and Merck announced their personalized cancer vaccine helped cut the recurrence of melanoma—a form of skin cancer—in a late-stage trial involving more than 1,100 patients, and that the experimental drug significantly extended the time patients lived without their melanoma returning.

The vaccine is an mRNA-based shot combined with Merck’s immunotherapy drug Keytruda, marking the first successful final-stage study for any mRNA-based cancer therapy.

Merck’s stock jumped 6.5% in early trading following the announcement.

112,000. That’s how many new cases of melanoma are diagnosed in the U.S. each year, with about 8,510 people expected to die of melanoma, according to the American Cancer Society. The group warned that lighter skin color is a major risk factor and that risk increases as people age.

The lowest level for Moderna’s stock came during its first trading session this year, dropping to $29.81 on Jan. 2 before surging nearly 300% to its premarket value on Wednesday.

Wall Street had anticipated results from Moderna’s latest mRNA vaccine, which have come under fire from Health and Human Services Secretary Robert F. Kennedy Jr. Kennedy, a noted vaccine skeptic who criticized mRNA COVID-19 vaccines like Moderna's, has said he would cancel contracts and grants worth nearly $500 million to develop such vaccines. Leerink Partners analyst Mani Foroohar wrote in June that results from Moderna’s late-stage trial would mark a make-or-break event for its stock, with expectations for the experimental medication to potentially work across multiple types of cancer. Merck and Moderna have said they are studying the vaccine in several trials of other tumors, like non-small cell lung cancer and bladder cancer.

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