Ocrevus Zunovo dosage: Form, strengths and more

Ocrevus Zunovo’s dosage for multiple sclerosis (MS) is typically 1 subcutaneous infusion every 6 months. Your dosing schedule may vary based on whether you have any active infections.

Ocrevus Zunovo’s active ingredients are ocrelizumab and hyaluronidase-ocsq. It’s a biologic drug that belongs to the monoclonal antibody drug class. (The reason “-ocsq” appears at the end of the drug’s name is to distinguish it from current or future biosimilar versions.)

This article describes the dosage of Ocrevus Zunovo, as well as its strength and how it’s given.

The following information describes the dosage that’s commonly used or recommended for Ocrevus Zunovo. Your doctor will determine the best dosage to fit your needs. In some cases, your doctor may adjust your dosage from those mentioned here.

Ocrevus Zunovo comes as a liquid solution in a single-use vial. It’s given as a subcutaneous infusion by your doctor or another healthcare professional.

Ocrevus Zunovo comes in one strength of 920 milligrams (mg) of ocrelizumab and 23,000 units of hyaluronidase in 23 milliliters (mL) of solution.

Ocrevus Zunovo is approved to treat CIS and certain types of MS in adults. The typical Ocrevus Zunovo dosage for these uses is 920 mg/23,000 units (1 vial) per infusion. You’ll receive 1 infusion every 6 months.

Ocrevus Zunovo is given as a subcutaneous infusion (an injection that’s given under your skin over a period of time) in your abdomen. Each infusion typically takes 10 minutes. It’s given by a doctor or another healthcare professional in a clinical setting, such as a hospital, doctor’s office, or infusion center.

Before starting Ocrevus Zunovo treatment, your doctor will order certain blood tests to check your risk of infection and liver health. They’ll also check if you have any active infections.

About 30 minutes before each infusion, your doctor will give you an oral corticosteroid, such as dexamethasone, and an antihistamine, such as desloratadine. This is to help prevent infusion reactions. Your doctor will also monitor you closely during and after the infusion for these side effects. Immediately tell your doctor if you experience swelling, a skin rash, or difficulty breathing. These symptoms can occur up to 24 hours after your infusion.

Ocrevus Zunovo is usually a long-term treatment. If you and your doctor determine that it’s safe and effective for your condition, you’ll likely receive it long term.

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.