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Uplizna and dosage: Strength, form, when to use, and more

Medical News Today Published Sep 16, 2025 Reviewed Jul 1, 2026 ✓ Reviewed by citations.press editors
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The typical Uplizna dosage for both conditions is 300mg, given by IV infusion.
300 mg · dose
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You’ll receive the first two doses of the drug 2 weeks apart.
2 weeks · interval between first two doses
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Then, you’ll receive your third dose of the drug 6 months after your first dose.
6 months · interval between first and third dose
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Typically, you’ll receive additional doses every 6 months.
6 months · interval between subsequent doses
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The prescribed dosage for Uplizna (inebilizumab-cdon) may vary depending on a person’s individual treatment plan. Other factors, including your specific diagnosis, body weight, and medical history, may affect your dosage of Uplizna.

Uplizna (inebilizumab-cdon) is a prescription drug used to treat certain autoimmune conditions. The drug comes as an intravenous (IV) infusion. The frequency of your infusions may vary based on your condition.

The active ingredient in Uplizna is inebilizumab-cdon. Uplizna belongs to a group of drugs called monoclonal antibody.

This article describes the dosages of Uplizna, as well as its strength and how to take it.

Your doctor will ultimately prescribe the dosage that provides the desired effect. Keep reading for more dosage details.

The following table highlights the basics of Uplizna’s dosage. All doses are listed in mg.

Your doctor will determine the best dosage to fit your needs. In some cases, doctors may adjust your dosage from those shown here.

Uplizna is approved to treat NMOSD and IgG4-RD. The typical Uplizna dosage for both conditions is 300mg, given by IV infusion. You’ll receive the first two doses of the drug 2 weeks apart. Then, you’ll receive your third dose of the drug 6 months after your first dose. Typically, you’ll receive additional doses every 6 months.

Always follow your prescribing doctor’s instructions. Notify them if you experience any side effects that may prevent you from taking your medication.

Uplizna is administered by a doctor, nurse, or other healthcare professional. You’ll typically receive Uplizna in a clinical setting, such as a hospital or infusion center.

Uplizna is usually a long-term treatment. If you and your doctor determine that it’s safe and effective for your condition, you’ll likely receive it long term.

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

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