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What do the brain ventricles do and what conditions do they relate to?

Medical News Today Published Nov 5, 2025 Reviewed Jul 1, 2026 ✓ Reviewed by citations.press editors
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The brain has four ventricles.
4 · ventricles
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The brain contains three basic units.
3 · basic units
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There are two lateral ventricles.
2 · lateral ventricles
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Each hemisphere has one lateral ventricle.
1 · right lateral ventricle1 · left lateral ventricle
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Each lateral ventricle has a capacity between 7 and 10 milliliters.
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The ventricles of the brain are four cavities that contain cerebrospinal fluid (CSF). Cells within these ventricles produce CSF, which helps to cushion the brain.

The brain contains three basic units. These are the forebrain, the midbrain, and the hindbrain.

The forebrain eventually becomes the cerebrum, which controls motor and sensory information. The midbrain develops into part of the brainstem, which controls autonomic functions such as breathing, and contacts fiber tracts that connect the cerebrum and cerebellum to the spinal cord. Part of the hindbrain eventually develops into the cerebellum, which controls the coordination of voluntary movement.

The brain also has the ventricular system, which consists of four ventricles. These ventricles are fluid-filled spaces that lie in the core of the forebrain and brainstem The ventricles are responsible for producing cerebrospinal fluid (CSF) and transporting it to the spinal cord.

The ventricles of the brain are four hollow channels. The brain’s ventricular system connects these ventricles together. It also connects them to the spinal cord.

The ventricles connect together via a series of holes and tubes. Medical professionals refer to the holes that connect the brain’s ventricles as foramen.

Each ventricle contains a specialized structure called the choroid plexus. Specialized ependymal cells within the choroid plexus create CSF.

CSF is a clear and colorless liquid that surrounds the brain and the spinal cord. This protects the brain and spinal cord by cushioning them. CSF also helps clear waste products from the brain and delivers nutrients to the brain. The ventricular system allows the CSF to travel through the brain to the spinal cord and back.

There are two lateral ventricles. There is one lateral ventricle present in the right hemisphere of the brain and one in the left. The lateral ventricles are C-shaped cavities. They each have a capacity of between 7 to 10 milliliters (ml).

A thin vertical sheet of nervous tissue separates the two lateral ventricles. Medical professionals refer to this sheet as the septum pellucidum. The two lateral ventricles connect to the third ventricle through a structure called the foramen of Munro.

The third ventricle is located in the center of the brain. It is a slit-shaped cavity. The thalamus and hypothalamus make up the walls of this ventricle.

The front and upper part of the third ventricle connects with the two lateral ventricles. This allows CSF to flow from the lateral ventricles into the third ventricle.

The back and lower part of the third ventricle connects to the fourth ventricle through a narrow channel called the aqueduct of Sylvius. This allows CSF to flow from the third ventricle into the fourth ventricle.

The fourth ventricle is a tent-shaped cavity in the hindbrain.

The fourth ventricle connects to the third ventricle through the aqueduct of Sylvius and connects to the spinal cord. This allows CFS to travel from the fourth ventricle to the spinal cord.

The ventricles in the brain produce CSF. Each ventricle houses a choroid plexus. This is a structure that consists of specialized ependymal cells. It is these cells that produce CSF. The ventricles also store CSF and circulate it around the brain and the spinal cord.

The brain’s ventricles also protect the brain by cushioning it. They are filled with CSF which acts as a shock absorber. This helps cushion the brain against the hard bones of the skull.

Hydrocephalus is a medical condition that occurs when a person experiences an unusual buildup of CSF in the brain. This can occur due to a tumor obstructing CSF flow, or an imfection or inflammation impairing CSF absorption. This excess CSF causes the ventricles to widen. This puts pressure on the brain’s tissue, which causes symptoms to occur.

Colloid brain cysts are slow-growing lesions that most commonly develop in the third ventricle. These cysts are benign. This means they are not cancerous. These cysts often develop close to Monro’s foramen.

In some cases, colloid cysts may lead to acute hydrocephalus and sudden death.

Dandy–Walker malformation is a rare brain condition that affects the cerebellum. The cerebellum is the part of the brain that controls movement and balance.

The malformation occurs in the back part of the brain. If a person has this malformation they will have a missing or underdeveloped middle section of the cerebellum. This section is the vermis.

When a person has the Dandy-Walker malformation they will develop an enlarged fourth ventricle. A cyst may form here pushing nearby brain structures upward. People with this malformation often develop hydrocephalus. The condition often causes delays in development or coordination.

Arnold-Chiari malformation is a condition that occurs due to problems involving the hindbrain. This can result in th cerebellum protruding downwards through the opening at the base of the skull.

In some cases, this may block the flow of CSF between the brain and the spine. This can cause the CSF to build up within the fourth ventricle. This may cause hydrocephalus to develop. Arnold-Chiari malformation can range from mild to severe. The severity often depends on how much of the brain protrudes downwards.

The brain has four ventricles. They produce and store CSF. CSF cushions the brain and spinal cord. It also delivers nutrients and removes waste.

The lateral ventricles sit in the left and right hemispheres. They connect to the third ventricle through the foramen of Munro. The third ventricle sits in the center of the brain. It links to the fourth ventricle via the aqueduct of Sylvius. The fourth ventricle also connects to the spinal cord.

Conditions like hydrocephalus, colloid cysts, Dandy-Walker malformation, and Arnold-Chiari malformation can affect the ventricles. Enlarged ventricles can damage brain tissue and disrupt CSF flow.

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