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› People › Samuel Sternberg
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Samuel Sternberg
3
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Science
science · Science Alert
The DRT3 system in Escherichia coli uses two different reverse transcriptases to independently generate the two complementary DNA strands.
“Rather than copying one DNA strand to make the other, as happens in normal DNA replication, the system uses two different reverse transcriptases to independently generate the two complementary strands”
2
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science · Science Alert
The DRT3b enzyme in Escherichia coli produces a repeating DNA sequence of six nucleotides: C-A-C-A-C-A.
“The result is an extraordinarily simple strand of DNA, consisting of the repeating sequence C-A-C-A-C-A”
6 nucleotides
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science · Science Alert
Altering the two amino acids in DRT3b that specify the DNA sequence disrupts both DNA synthesis and the bacterium's antiviral defense.
“When they did, both DNA synthesis and the bacterium's antiviral defense broke down, confirming that the amino acids were critical to the process”
2 amino acids
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